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http://dx.doi.org/10.18419/opus-12432
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DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Stiefvatter, Lena | - |
dc.contributor.author | Lehnert, Katja | - |
dc.contributor.author | Frick, Konstantin | - |
dc.contributor.author | Montoya-Arroyo, Alexander | - |
dc.contributor.author | Frank, Jan | - |
dc.contributor.author | Vetter, Walter | - |
dc.contributor.author | Schmid-Staiger, Ulrike | - |
dc.contributor.author | Bischoff, Stephan C. | - |
dc.date.accessioned | 2022-10-07T08:44:44Z | - |
dc.date.available | 2022-10-07T08:44:44Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1660-3397 | - |
dc.identifier.other | 1823209025 | - |
dc.identifier.uri | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-ds-124514 | de |
dc.identifier.uri | http://elib.uni-stuttgart.de/handle/11682/12451 | - |
dc.identifier.uri | http://dx.doi.org/10.18419/opus-12432 | - |
dc.description.abstract | The microalgae Phaeodactylum tricornutum (PT) contains valuable nutrients such as proteins, polyunsaturated omega-3 fatty acids (n-3 PUFA), particularly eicosapentaenoic acid (EPA) and some docosahexaenoic acid (DHA), carotenoids such as fucoxanthin (FX), and beta-glucans, which may confer health benefits. In a randomized intervention trial involving 22 healthy individuals, we administered for two weeks in a crossover manner the whole biomass of PT (5.3 g/day), or fish oil (FO) containing equal amounts of EPA and DHA (together 300 mg/day). In an additional experiment, sea fish at 185 g/week resulting in a similar EPA and DHA intake was administered in nine individuals. We determined the bioavailability of fatty acids and carotenoids and assessed safety parameters. The intake of PT resulted in a similar increase in the n-3 PUFA and EPA content and a decrease in the PUFA n-6:n-3 ratio in plasma. PT intake caused an uptake of FX that is metabolized to fucoxanthinol (FXOH) and amarouciaxanthin A (AxA). No relevant adverse effects occurred following PT consumption. The study shows that PT is a safe and effective source of EPA and FX—and likely other nutrients—and therefore should be considered as a future sustainable food item. | en |
dc.language.iso | en | de |
dc.relation.uri | doi:10.3390/md19120700 | de |
dc.rights | info:eu-repo/semantics/openAccess | de |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | de |
dc.subject.ddc | 570 | de |
dc.title | Oral bioavailability of omega-3 fatty acids and carotenoids from the microalgae Phaeodactylum tricornutum in healthy young adults | en |
dc.type | article | de |
dc.date.updated | 2022-01-03T18:47:47Z | - |
ubs.fakultaet | Energie-, Verfahrens- und Biotechnik | de |
ubs.fakultaet | Externe wissenschaftliche Einrichtungen | de |
ubs.fakultaet | Fakultätsübergreifend / Sonstige Einrichtung | de |
ubs.institut | Institut für Grenzflächenverfahrenstechnik und Plasmatechnologie | de |
ubs.institut | Fraunhofer Institut für Grenzflächen- und Bioverfahrenstechnik (IGB) | de |
ubs.institut | Fakultätsübergreifend / Sonstige Einrichtung | de |
ubs.publikation.seiten | 19 | de |
ubs.publikation.source | Marine drugs 19 (2021), No. 700 | de |
ubs.publikation.typ | Zeitschriftenartikel | de |
Enthalten in den Sammlungen: | 04 Fakultät Energie-, Verfahrens- und Biotechnik |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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marinedrugs-19-00700.pdf | 1,75 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons