Bitte benutzen Sie diese Kennung, um auf die Ressource zu verweisen:
http://dx.doi.org/10.18419/opus-13215
Langanzeige der Metadaten
| DC Element | Wert | Sprache |
|---|---|---|
| dc.contributor.author | Rathert, Philipp | - |
| dc.date.accessioned | 2023-06-26T12:10:36Z | - |
| dc.date.available | 2023-06-26T12:10:36Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.issn | 2075-1729 | - |
| dc.identifier.other | 1852089296 | - |
| dc.identifier.uri | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-ds-132346 | de |
| dc.identifier.uri | http://elib.uni-stuttgart.de/handle/11682/13234 | - |
| dc.identifier.uri | http://dx.doi.org/10.18419/opus-13215 | - |
| dc.description.abstract | NSD3 is one of six H3K36-specific lysine methyltransferases in metazoans, and the methylation of H3K36 is associated with active transcription. NSD3 is a member of the nuclear receptor-binding SET domain (NSD) family of histone methyltransferases together with NSD1 and NSD2, which generate mono- and dimethylated lysine on histone H3. NSD3 is mutated and hyperactive in some human cancers, but the biochemical mechanisms underlying such dysregulation are barely understood. In this review, the current knowledge of NSD3 is systematically reviewed. Finally, the molecular and functional characteristics of NSD3 in different tumor types according to the current research are summarized. | en |
| dc.language.iso | en | de |
| dc.relation.uri | doi:10.3390/life11080726 | de |
| dc.rights | info:eu-repo/semantics/openAccess | de |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | de |
| dc.subject.ddc | 540 | de |
| dc.subject.ddc | 570 | de |
| dc.title | Structure, activity and function of the NSD3 protein lysine methyltransferase | en |
| dc.type | article | de |
| dc.date.updated | 2021-08-01T18:16:36Z | - |
| ubs.fakultaet | Chemie | de |
| ubs.institut | Institut für Biochemie und Technische Biochemie | de |
| ubs.publikation.seiten | 13 | de |
| ubs.publikation.source | Life 11 (2021), No. 726 | de |
| ubs.publikation.typ | Zeitschriftenartikel | de |
| Enthalten in den Sammlungen: | 03 Fakultät Chemie | |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| life-11-00726-v2.pdf | 2,24 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons
