Strongly pairing ethynylpyridone C‐nucleosides are attractive surrogates for thymidine in oligonucleotides. Exploratory work on the antiviral activity of 3′‐azidothymidine (AZT) derivatives with ethynylpyridone as base had identified strong lipophilicity as a limiting factor. Two strategies are being pursued&#x...

Deposit formation and fouling in reactors for polymer production and processing especially in microreactors is a well‐known phenomenon. Despite the flow and pressure loss optimized static mixers, fouling occurs on the surfaces of the mixer elements. To improve the performance of such pa...

Herein, the first stable anions K[SIPrBp] (4 a‐K) and K[IPrBp] (4 b‐K) (SIPrBp=BpC{N(Dipp)CH2}2, IPrBp=BpC{N(Dipp)CH}2; Bp=4‐PhC6H4; Dipp=2,6‐iPr2C6H3) derived from classical N‐heterocyclic carbenes (NHCs) (i.e. SIPr and IPr) have been isolated as violet crystalline solids. 4 a‐K and 4 b‐K are prepared by KC8&#...

Das Bestreben nach sauberen Fahrzeugen mit verbrennungsmotorischem Antrieb erfordert den emissionssicheren Betrieb des Motors im gesamten Kennfeld und während jeder Betriebssituation. Die nachmotorische Stickoxid (NOx)-Reduzierung benötigt ein gewisses Temperaturniveau. Bei einem NOx-Speicherkatalysator (NSK) liegt diese ...

Die Halbleiter-Spintronik beschäftigt sich mit der Entwicklung neuer Bauelementkonzepte, die den intrinsischen Spin-Freiheitsgrad des Elektrons ausnutzen. Dabei werden spin-basierte Logik-Bauelemente aufgrund des geringen Energiebedarfs zum Umschalten der Spin-Orientierung als aussichtsreiche Kandidaten für zukünftige Transistor-A...

Zukünftige Antriebssysteme werden immer komplexer. Beispielsweise ergeben sich durch die Hybridisierung von Verbrennungsmotoren umfangreiche Möglichkeiten für die Leistungsaufteilung im Triebstrang, welche in Kombination mit der Auslegung eines darauf angepassten Brennverfahrens zahlreiche Abstimmparameter enthält. Zudem sind...

The political and social aspiration to reduce greenhouse gases together with increasing energy demands are driving the development of new sustainable energy solutions. To achieve long term sustainability both innovative energy sources and improvements in efficiency are essential. Higher process e...

Research on building information modelling (BIM) for corporate real estate management (CREM) in the chemical industry remains limited. This is largely due to a lack of documents supporting BIM adoption and implementation. The present study identifies, compares, and applies different approaches&#x...

Trotz der vielen akuten Krisen die letzten Jahre, die jeweils die volle Aufmerksamkeit fordern: Die zunehmende Häufigkeit extremer Wetterereignisse - Dürren, Stürme, Überschwemmungen, extreme Hitze und Kälte - macht deutlich, dass die Zeit zur Eindämmung der Klimakrise knapp wird. In dieser ...

An attractive solution to produce carbon-based chemicals is to utilize CO2 as raw material and renewable electricity as energy source for its activation such as in the reduction of CO2 (CO2RR) into formate salts. In the course of this work, carbon-based and PTFE-bound gas-diffusion...

Controlling the pairing strength of nucleobases in DNA through reactions with compounds found inside the cell is a formidable challenge. Here we report how a thiazolyl substituent turns a strongly pairing ethynylpyridone C‐nucleoside into a reactive residue in oligonucleotides. The thiazolyl‐bear...

Usually, end milling operations have been carried out using conventional uniform helix tools with fixed helix angles. Thus, many studies have been conducted to study the effects of these tools on the thermomechanical properties of a milling process. Recently, there have been works ...

The effect of vibration on the condition of sensitive works of art continues to be of great importance to museums. Vibrations contribute to irreversible changes in the complex materiality of art and cultural heritage. In cooperation with the Klassik Stiftung Weimar, the Institute o...

A series of low‐temperature studies on LiNi0.80Co0.15Al0.05O2 18650‐type batteries of high‐energy type with different stabilized states of fatigue is carried out using spatially resolved neutron powder diffraction, infrared/thermal imaging, and quasi‐adiabatic calorimetry. In‐plane distribution of lithium in&#x...

The thermodiffusion behavior of binary Lennard‐Jones mixtures in the liquid state is investigated by combining the individual strengths of non‐equilibrium molecular dynamics (NEMD) and equilibrium molecular dynamics (EMD) simulations. On the one hand, boundary‐driven NEMD simulations are useful to qui...

Researchers are spending an increasing fraction of their time on applying for funding; however, the current funding system has considerable deficiencies in reliably evaluating the merit of research proposals, despite extensive efforts on the sides of applicants, grant reviewers and decision ...

The effect of fatigue failure in brittle materials like (ultra) High Performance Concrete (UHPC) due to cyclic loading causes unexpected failure that consequently results in heavy costs in marine and civil structures. To characterize the effect of fatigue, cyclic loading tests are perfo...