Xin, LingDuan, XiaoyangLiu, Na2023-05-252023-05-2520212041-17231846920388http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-ds-130852http://elib.uni-stuttgart.de/handle/11682/13085http://dx.doi.org/10.18419/opus-13066In living organisms, proteins are organized prevalently through a self-association mechanism to form dimers and oligomers, which often confer new functions at the intermolecular interfaces. Despite the progress on DNA-assembled artificial systems, endeavors have been largely paid to achieve monomeric nanostructures that mimic motor proteins for a single type of motion. Here, we demonstrate a DNA-assembled building block with rotary and walking modules, which can introduce new motion through dimerization and oligomerization. The building block is a chiral system, comprising two interacting gold nanorods to perform rotation and walking, respectively. Through dimerization, two building blocks can form a dimer to yield coordinated sliding. Further oligomerization leads to higher-order structures, containing alternating rotation and sliding dimer interfaces to impose structural twisting. Our hierarchical assembly scheme offers a design blueprint to construct DNA-assembled advanced architectures with high degrees of freedom to tailor the optical responses and regulate multi-motion on the nanoscale.eninfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/530570article2023-03-28