Barth, StefanEffenberger, Franz2009-08-282016-03-312009-08-282016-03-311993316226270http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-44477http://elib.uni-stuttgart.de/handle/11682/1183http://dx.doi.org/10.18419/opus-1166(R)-2-alkyl-1-alkanoids (R)-1 with high optical purities were obtained by lipase-catalyzed esterification of the racemic substrates (R,S)-1 with vinyl acetate in dichloromethane. The alcohols (R)-1 were oxidized without racemization to the corresponding carboxylic acids (R)-4. The enriched (S)-acetates (S)-3 either were saponified to the alcohols (S)-1 which are substrates for a second lipase-catalyzed transesterification to give (S)-1 in high optical purity or were racemized and applied once again in the kinetic resolution to prepare (R)-1.eninfo:eu-repo/semantics/openAccessAlkanole , Enzymkatalyse , Racemisierung540article