Dertinger, HermannHülser, Dieter F.Hinz, Gudrun2011-10-242016-03-312011-10-242016-03-31197935685213Xhttp://nbn-resolving.de/urn:nbn:de:bsz:93-opus-68152http://elib.uni-stuttgart.de/handle/11682/1937http://dx.doi.org/10.18419/opus-1920Multicell spheroids (SPH) offer unique advantages for studying modifications of single cell radiosensitivity due to the extensive intercellular communication in a three-dimensionally organized tissue. We have been able to relate the increased radio-resistance of spheroid cells as compared to monolayer (ML) cells ("Contact Resistance") to the degree of ionic coupling between the cells as measured by a micro-electrode technique.eninfo:eu-repo/semantics/openAccessZellkultur , Zellkommunikation , Mikroelektrode570Survival and chromosome injury of spheroid cells after irradiationarticle