Büttner, DietmarHackbarth, HansjoachimWollnik, FranziskaBorggreve, H.2014-05-212016-03-312014-05-212016-03-311984412009684http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-92912http://elib.uni-stuttgart.de/handle/11682/8235http://dx.doi.org/10.18419/opus-8218Systolic blood pressure was measured in males of 8 inbred strains and 1 outbred stock of rats 5 times over a period of 20 min on 5 consecutive days. The strain means ranged between 107·9 mmHg and 149·3 mmHg. The estimated variance between strains (V = 248·7 mmHg) was about 5 times higher than the variance within strains (V = 54·3 mmHg). The intraindividual variance within strains was relatively constant (V = 24·0-37·6 mmHg), while the interindividual variance varied to a great extent (V = 4·5-44·5 mmHg) from strain to strain. The outbred stock showed values of blood pressure and components of variance similar to those of a single inbred strain. Thus, by investigation of a battery of 8 inbred strains in a multifactorial experimental design a greater phenotypic variability due to genetic strain differences is achieved than by measurements in a single outbred stock.eninfo:eu-repo/semantics/openAccessBlutdruck , Züchtung , Ratte590Blood pressure in rats : a comparison of a multifactorial experimental design to measurements in an outbred stockarticle2014-08-20