Browsing by Author "Schrank, Paul"

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    Identification of the first sulfobetaine hydrogel‐binding peptides via phage display assay
    (2023) Ihlenburg, Ramona B. J.; Petracek, David; Schrank, Paul; Davari, Mehdi D.; Taubert, Andreas; Rothenstein, Dirk
    Using the M13 phage display, a series of 7- and 12-mer peptides which interact with new sulfobetaine hydrogels are identified. Two peptides each from the 7- and 12-mer peptide libraries bind to the new sulfobetaine hydrogels with high affinity compared to the wild-type phage lacking a dedicated hydrogel binding peptide. This is the first report of peptides binding to zwitterionic sulfobetaine hydrogels and the study therefore opens up the pathway toward new phage or peptide/hydrogel hybrids with high application potential.