Bitte benutzen Sie diese Kennung, um auf die Ressource zu verweisen:
http://dx.doi.org/10.18419/opus-1112
Langanzeige der Metadaten
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Effenberger, Franz | de |
dc.contributor.author | Zoller, Gerhard | de |
dc.date.accessioned | 2009-07-30 | de |
dc.date.accessioned | 2016-03-31T07:47:40Z | - |
dc.date.available | 2009-07-30 | de |
dc.date.available | 2016-03-31T07:47:40Z | - |
dc.date.issued | 1988 | de |
dc.identifier.other | 316155160 | de |
dc.identifier.uri | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-43550 | de |
dc.identifier.uri | http://elib.uni-stuttgart.de/handle/11682/1129 | - |
dc.identifier.uri | http://dx.doi.org/10.18419/opus-1112 | - |
dc.description.abstract | The alkoxide-catalyzed addition of alcohols to α-chloroacrylonitrile at -35°C gives rise to 3-alkoxy-2-chloropropanenitriles; at 0–5°C with excess alkyl 3-alkoxy-2-chloropropanimidates are obtained. The yields of 3 or 4 decrease with increasing pKa values of the alcohols. In the base-catalyzed addition of phenols 5 to 1, a temperature-dependent addition equilibrium is set up in which the position of equilibrium is shifted in favour of the addition products with increasing pKa values of 5. The 3-alkoxy-2-chloropropanoates, which are readily accessible by hydrolysis of 4, react smoothly with sodium azide in the presence of a phase transfer catalyst to furnish the 3-alkoxy-2-azidopropanoates. Starting from benzyl 2-azido-3-benzyloxy-propanoate (10b), the specific syntheses of DL-serine (14), DL-serine hydrochloride (14·HCl), DL-serine methyl ester hydrochloride (13a·HCl), 0-benzyl-DL-serine (12b), and 0-benzyl-DL-serine benzyl ester hydrochloride (11b·HCl) are possible by variation of the hydrogenation conditions. | en |
dc.language.iso | en | de |
dc.rights | info:eu-repo/semantics/openAccess | de |
dc.subject.classification | Aminosäuren , Serin | de |
dc.subject.ddc | 540 | de |
dc.title | Investigations on the synthesis of DL-serine from α-haloacrylic acid derivatives (Aminoacids ; 13) | en |
dc.type | article | de |
dc.date.updated | 2013-06-14 | de |
ubs.fakultaet | Fakultät Chemie | de |
ubs.institut | Institut für Organische Chemie | de |
ubs.opusid | 4355 | de |
ubs.publikation.source | Tetrahedron 44 (1988), S. 5573-5582. URL http://dx.doi.org./10.1016/S0040-4020(01)86062-2 | de |
ubs.publikation.typ | Zeitschriftenartikel | de |
Enthalten in den Sammlungen: | 03 Fakultät Chemie |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
---|---|---|---|---|
eff188.pdf | 795,07 kB | Adobe PDF | Öffnen/Anzeigen |
Alle Ressourcen in diesem Repositorium sind urheberrechtlich geschützt.