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http://dx.doi.org/10.18419/opus-12432
Autor(en): | Stiefvatter, Lena Lehnert, Katja Frick, Konstantin Montoya-Arroyo, Alexander Frank, Jan Vetter, Walter Schmid-Staiger, Ulrike Bischoff, Stephan C. |
Titel: | Oral bioavailability of omega-3 fatty acids and carotenoids from the microalgae Phaeodactylum tricornutum in healthy young adults |
Erscheinungsdatum: | 2021 |
Dokumentart: | Zeitschriftenartikel |
Seiten: | 19 |
Erschienen in: | Marine drugs 19 (2021), No. 700 |
URI: | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-ds-124514 http://elib.uni-stuttgart.de/handle/11682/12451 http://dx.doi.org/10.18419/opus-12432 |
ISSN: | 1660-3397 |
Zusammenfassung: | The microalgae Phaeodactylum tricornutum (PT) contains valuable nutrients such as proteins, polyunsaturated omega-3 fatty acids (n-3 PUFA), particularly eicosapentaenoic acid (EPA) and some docosahexaenoic acid (DHA), carotenoids such as fucoxanthin (FX), and beta-glucans, which may confer health benefits. In a randomized intervention trial involving 22 healthy individuals, we administered for two weeks in a crossover manner the whole biomass of PT (5.3 g/day), or fish oil (FO) containing equal amounts of EPA and DHA (together 300 mg/day). In an additional experiment, sea fish at 185 g/week resulting in a similar EPA and DHA intake was administered in nine individuals. We determined the bioavailability of fatty acids and carotenoids and assessed safety parameters. The intake of PT resulted in a similar increase in the n-3 PUFA and EPA content and a decrease in the PUFA n-6:n-3 ratio in plasma. PT intake caused an uptake of FX that is metabolized to fucoxanthinol (FXOH) and amarouciaxanthin A (AxA). No relevant adverse effects occurred following PT consumption. The study shows that PT is a safe and effective source of EPA and FX—and likely other nutrients—and therefore should be considered as a future sustainable food item. |
Enthalten in den Sammlungen: | 04 Fakultät Energie-, Verfahrens- und Biotechnik |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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marinedrugs-19-00700.pdf | 1,75 MB | Adobe PDF | Öffnen/Anzeigen |
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