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Authors: Engesser, Karl-Heinrich
Schulte, P.
Title: Degradation of 2-bromo-, 2-chloro- and 2-fluorobenzoate by Pseudomonas putida CLB 250
Issue Date: 1989 Zeitschriftenartikel FEMS microbiology letters 60 (1989), S. 143-147. URL http://dx.doi.oerg./10.1111/j.1574-6968.1989.tb03434.x
Abstract: Pseudomonas putida strain CLB 250 (DSM 5232) utilized 2-bromo-, 2-chloro- and 2-fluorobenzoate as sole source of carbon and energy. Degradation is suggested to be initiated by a dioxygenase liberating halide in the first catabolic step. After decarboxylation and rearomatization catechol is produced as a central metabolite which is degraded via the ortho-pathway. After inhibition of ring cleavage activities with 3-chlorocatechol, 2-chlorobenzoate was transformed to catechol in nearly stoichiometric amounts. Other ortho-substituted benzoates like anthranilate and 2-methoxybenzoate seem to be metabolized via the same route.
Appears in Collections:04 Fakultät Energie-, Verfahrens- und Biotechnik

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