15 Fakultätsübergreifend / Sonstige Einrichtung

Permanent URI for this collectionhttps://elib.uni-stuttgart.de/handle/11682/16

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Institute: search.filters.UBSInstitut.Institut für Biomaterialien und biomolekulare SystemeAuthor: search.filters.author.Hauber, Wolfgang

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Now showing 1 - 3 of 3
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    Differential effects of lesions of the dorsomedial and dorsolateral caudate putamen on reaction time performance in rats
    (1994) Hauber, Wolfgang; Schmidt, Werner J.
    In order to investigate the role of the dorsomedial and dorsolateral caudate-putamen (CPu) in movement initiation of rats, we examined the effects of quinolinic acid lesions (30 nmol in 1 μl) in these striatal subregions in a simple reaction time task. Results show that lesions of the dorsomedial, but not of the dorsolateral CPu increased reaction times. These findings provide further evidence for a functional heterogenity of the CPu and demonstrate an involvement of the dorsomedial CPu in processes related to rapid initiation of responses
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    Role of the medial orbitofrontal cortex and ventral tegmental area in effort-related responding
    (2020) Münster, Alexandra; Votteler, Angeline; Sommer, Susanne; Hauber, Wolfgang
    Die Arbeit untersucht die Interaktion von zwei Gehirnarealen, dem medialen Orbitofrontalcortex und dem Ventralen Tegmentalen Areal, bei der Handlungssteuerung.
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    Behavioural pharmacology of glutamate in the basal ganglia
    (1992) Schmidt, Werner J.; Bubser, Michael; Hauber, Wolfgang
    In Parkinson's disease the dopaminergic inhibition - mediated by DA2 receptors in the triatum - is reduced. Therefore glutamatergic excitation predominates in the antero-dorsal striatum. In turn the glutamatergic neurons of the subthalamic nucleus become disinhibited. Antagonists of the NMDAsubtype of glutamate receptor injected locally into the glutamatergically innervated nuclei or competitive and non-competitive NMDA-antagonista administered systemically, counteract parkinsonian symptom in animals.