15 Fakultätsübergreifend / Sonstige Einrichtung
Permanent URI for this collectionhttps://elib.uni-stuttgart.de/handle/11682/16
Browse
4 results
Search Results
Item Open Access Comparative sensitivity analysis of muscle activation dynamics(2015) Rockenfeller, Robert; Günther, Michael; Schmitt, Syn; Götz, ThomasWe mathematically compared two models of mammalian striated muscle activation dynamics proposed by Hatze and Zajac. Both models are representative for a broad variety of biomechanical models formulated as ordinary differential equations (ODEs). These models incorporate parameters that directly represent known physiological properties. Other parameters have been introduced to reproduce empirical observations. We used sensitivity analysis to investigate the influence of model parameters on the ODE solutions. In addition, we expanded an existing approach to treating initial conditions as parameters and to calculating second- order sensitivities. Furthermore, we used a global sensitivity analysis approach to include finite ranges of parameter values. Hence, a theoretician striving for model reduction could use the method for identifying particularly low sensitivities to detect superfluous parameters. An experimenter could use it for identifying particularly high sensitivities to improve parameter estimation. Hatze’s nonlinear model incorporates some parameters to which activation dynamics is clearly more sensitive than to any parameter in Zajac’s linear model. Other than Zajac’s model, Hatze’s model can, however, reproduce measured shifts in optimal muscle length with varied muscle activity. Accordingly we extracted a specific parameter set for Hatze’s model that combines best with a particular muscle force-length relation.Item Open Access Walkability is only part of the story : walking for transportation in Stuttgart, Germany(2014) Reyer, Maren; Fina, Stefan; Siedentop, Stefan; Schlicht, WolfgangIn modern Western societies people often lead inactive and sedentary lifestyles, even though there is no doubt that physical activity and health are related. From an urban planning point of view it would be highly desirable to develop built environments in a way that supports people in leading more active and healthy lifestyles. Within this context there are several methods, predominantly used in the US, to measure the suitability of built environments for walking and cycling. Empirical studies show that people living in highly walkable areas are more physically active (for example, walk more or cycle more). The question is, however, whether these results are also valid for European cities given their different urban planning characteristics and infrastructure standards. To answer this question we used the Walkability-Index and the Walk Score to empirically investigate the associations between walkability and active transportation in the city of Stuttgart, Germany. In a sample of household survey data (n = 1.871) we found a noticeable relationship between walkability and active transportation—the more walkable an area was, the more active residents were. Although the statistical effect is small, the health impact might be of relevance. Being physically active is multi-determined and not only affected by the walkability of an area. We highlight these points with an excursion into research that the health and exercise sciences contribute to the topic. We propose to strengthen interdisciplinary research between the disciplines and to specifically collect data that captures the influence of the environment on physical activity in the future.Item Open Access Stuttgart in Bewegung - Berichte von unterwegs(Berlin : jovis, 2018) Gantert, Marius; Stokman, AntjeStuttgart ohne Feinstaub, lärmende Straßen und zugeparkte Plätze. Mit lebendigen Nachbarschaften, einladenden öffentlichen Räumen, selbstbestimmter Mobilität und gesellschaftlicher Teilhabe für Jung und Alt. Wie könnte eine solche Transformation gelingen? Der aktuell viel diskutierte Ansatz der Reallabor-Forschung in Verbindung mit dem Praxisbeispiel des Stuttgarter Reallabors für nachhaltige Mobilitätskultur gibt Antworten darauf. Ziel des Stuttgarter Reallabors ist die Etablierung einer Mobilitätskultur, die nicht nur Ressourcen schont, sondern auch Gesundheit und körperliche Bewegung unterstützt, soziale Interaktion fördert und in Stadt und Region neue Lebens- und Aufenthaltsqualitäten schafft. Durch gemeinsam gestaltete Realexperimente vom Handeln zum Wissen zu kommen - so lautet der Grundsatz. Dazu haben BürgerInnen zusammen mit WissenschaftlerInnen und Studierenden geforscht, experimentiert sowie Denkanstöße, Praktiken und Visionen entwickelt. Aus der Perspektive der verschiedenen Projektbeteiligten zeichnet das Buch ein lebendiges Bild des Reallabors, von seinem Aufbau bis zur ko-produktiven Umsetzung von Realexperimenten, in der Verknüpfung von Theorien, Methoden, Ergebnissen, Erfahrungen und Eindrücken. Die Stadt wird zu einem Möglichkeits- und Experimentierraum für neue Formen des gegenseitigen Lernens und der Gestaltung nachhaltiger Transformationsprozesse.Item Open Access Theoretical hill-type muscle and stability : numerical model and application(2013) Schmitt, Syn; Günther, Michael; Rupp, Tille; Bayer, Alexandra; Häufle, Daniel F. B.The construction of artificial muscles is one of the most challenging developments in today's biomedical science. The application of artificial muscles is focused both on the construction of orthotics and prosthetics for rehabilitation and prevention purposes and on building humanoid walking machines for robotics research. Research in biomechanics tries to explain the functioning and design of real biological muscles and therefore lays the fundament for the development of functional artificial muscles. Recently, the hyperbolic Hill-type force-velocity relation was derived from simple mechanical components. In this contribution, this theoretical yet biomechanical model is transferred to a numerical model and applied for presenting a proof-of-concept of a functional artificial muscle. Additionally, this validated theoretical model is used to determine force-velocity relations of different animal species that are based on the literature data from biological experiments. Moreover, it is shown that an antagonistic muscle actuator can help in stabilising a single inverted pendulum model in favour of a control approach using a linear torque generator.