15 Fakultätsübergreifend / Sonstige Einrichtung

Permanent URI for this collectionhttps://elib.uni-stuttgart.de/handle/11682/16

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1993 - 199912010 - 20152

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Publication Type: search.filters.UBSTyp.ZeitschriftenartikelAuthor: search.filters.author.Günther, Michael

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Now showing 1 - 3 of 3
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    Comparative sensitivity analysis of muscle activation dynamics
    (2015) Rockenfeller, Robert; Günther, Michael; Schmitt, Syn; Götz, Thomas
    We mathematically compared two models of mammalian striated muscle activation dynamics proposed by Hatze and Zajac. Both models are representative for a broad variety of biomechanical models formulated as ordinary differential equations (ODEs). These models incorporate parameters that directly represent known physiological properties. Other parameters have been introduced to reproduce empirical observations. We used sensitivity analysis to investigate the influence of model parameters on the ODE solutions. In addition, we expanded an existing approach to treating initial conditions as parameters and to calculating second- order sensitivities. Furthermore, we used a global sensitivity analysis approach to include finite ranges of parameter values. Hence, a theoretician striving for model reduction could use the method for identifying particularly low sensitivities to detect superfluous parameters. An experimenter could use it for identifying particularly high sensitivities to improve parameter estimation. Hatze’s nonlinear model incorporates some parameters to which activation dynamics is clearly more sensitive than to any parameter in Zajac’s linear model. Other than Zajac’s model, Hatze’s model can, however, reproduce measured shifts in optimal muscle length with varied muscle activity. Accordingly we extracted a specific parameter set for Hatze’s model that combines best with a particular muscle force-length relation.
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    Interactive control of biomechanical animation
    (1993) Ertl, Thomas; Ruder, Hanns; Allrutz, Ralf; Gruber, Karin; Günther, Michael; Hospach, Frank; Ruder, Margret; Subke, Jörg; Widmayer, Karin
    Physics-based animation can be generated by performing a complete dynamical simulation of multibody systems. This leads to the solving of a complex system of differential equations in which biomechanical results for the physics of impacts are incorporated. Motion control is achieved by interactively modifying the internal torques. Realtime response requires the distribution of the workload of the computation between a high-speed compute server and the graphics workstation by means of a remote-procedure call mechanism.
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    Theoretical hill-type muscle and stability : numerical model and application
    (2013) Schmitt, Syn; Günther, Michael; Rupp, Tille; Bayer, Alexandra; Häufle, Daniel F. B.
    The construction of artificial muscles is one of the most challenging developments in today's biomedical science. The application of artificial muscles is focused both on the construction of orthotics and prosthetics for rehabilitation and prevention purposes and on building humanoid walking machines for robotics research. Research in biomechanics tries to explain the functioning and design of real biological muscles and therefore lays the fundament for the development of functional artificial muscles. Recently, the hyperbolic Hill-type force-velocity relation was derived from simple mechanical components. In this contribution, this theoretical yet biomechanical model is transferred to a numerical model and applied for presenting a proof-of-concept of a functional artificial muscle. Additionally, this validated theoretical model is used to determine force-velocity relations of different animal species that are based on the literature data from biological experiments. Moreover, it is shown that an antagonistic muscle actuator can help in stabilising a single inverted pendulum model in favour of a control approach using a linear torque generator.