07 Fakultät Konstruktions-, Produktions- und Fahrzeugtechnik
Permanent URI for this collectionhttps://elib.uni-stuttgart.de/handle/11682/8
Browse
7 results
Search Results
Item Open Access Depth from axial differential perspective(2022) Faulhaber, Andreas; Krächan, Clara; Haist, TobiasWe introduce an imaging-based passive on-axis technique for measuring the distance of individual objects in complex scenes. Two axially separated pupil positions acquire images (can be realized simultaneously or sequentially). Based on the difference in magnification for objects within the images, the distance to the objects can be inferred. The method avoids some of the disadvantages of passive triangulation sensors (e.g., correspondence, shadowing), is easy to implement and offers high lateral resolution. Due to the principle of operation it is especially suited for applications requiring only low to medium axial resolution. Theoretical findings, as well as follow-up experimental measurements, show obtainable resolutions in the range of few centimeters for distances of up to several meters.Item Open Access Enzyme-assisted circular additive manufacturing as an enabling technology for a circular bioeconomy : a conceptual review(2024) Protte-Freitag, Kristin; Gotzig, Sophia; Rothe, Hannah; Schwarz, Oliver; Silber, Nadine; Miehe, RobertAdditive manufacturing (AM) is a decisive element in the sustainable transformation of technologies. And yet its inherent potential has not been fully utilized. In particular, the use of biological materials represents a comparatively new dimension that is still in the early stages of deployment. In order to be considered sustainable and contribute to the circular economy, various challenges need to be overcome. Here, the literature focusing on sustainable, circular approaches is reviewed. It appears that existing processes are not yet capable of being used as circular economy technologies as they are neither able to process residual and waste materials, nor are the produced products easily biodegradable. Enzymatic approaches, however, appear promising. Based on this, a novel concept called enzyme-assisted circular additive manufacturing was developed. Various process combinations using enzymes along the process chain, starting with the preparation of side streams, through the functionalization of biopolymers to the actual printing process and post-processing, are outlined. Future aspects are discussed, stressing the necessity for AM processes to minimize or avoid the use of chemicals such as solvents or binding agents, the need to save energy through lower process temperatures and thereby reduce CO2 consumption, and the necessity for complete biodegradability of the materials used.Item Open Access Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines(2017) Jensch, Antje; Thomaseth, Caterina; Radde, NicolePositive and negative feedback loops are ubiquitous motifs in biochemical signaling pathways. The mitogen-activated protein kinase (MAPK) pathway module is part of many distinct signaling networks and comprises several of these motifs, whose functioning depends on the cell line at hand and on the particular context. The maintainance of specificity of the response of the MAPK module to distinct stimuli has become a key paradigm especially in PC-12 cells, where the same module leads to different cell fates, depending on the stimulating growth factor. This cell fate is regulated by differences in the ERK (MAPK) activation profile, which shows a transient response upon stimulation with EGF, while the response is sustained in case of NGF. This behavior was explained by different effective network topologies. It is widely believed that this sustained response requires a bistable system. In this study we present a sampling-based Bayesian model analysis on a dataset, in which PC-12 cells have been stimulated with different growth factors. This is combined with novel analysis methods to investigate the role of feedback interconnections to shape ERK response. Results strongly suggest that, besides bistability, an additional effect called quasi-bistability can contribute to explain the observed responses of the system to different stimuli. Quasi-bistability is the ability of a monostable system to maintain two distinct states over a long time period upon a transient signal, which is also related to positive feedback, but cannot be detected by standard steady state analysis methods.Item Open Access Experimental analysis on CPA-free thin-disk multipass amplifiers operated in a helium-rich atmosphere(2022) Bienert, Florian; Loescher, André; Röcker, Christoph; Graf, Thomas; Abou Ahmed, MarwanEs wird der Einfluss von Helium als atmosphärisches Gas in Scheibenlaser-multipass-Ultrakurzpulsverstärkern untersucht.Item Open Access The effect of rod orientation on electrical anisotropy in silver nanowire networks for ultra-transparent electrodes(2016) Ackermann, Thomas; Neuhaus, Raphael; Roth, SiegmarTwo-dimensional networks made of metal nanowires are excellent paradigms for the experimental observation of electrical percolation caused by continuous jackstraw-like physical pathways. Such systems became very interesting as alternative material in transparent electrodes, which are fundamental components in display devices. This work presents the experimental characterization of low-haze and ultra-transparent electrodes based on silver nanowires. The films are created by dip-coating, a feasible and scalable liquid film coating technique. We have found dominant alignment of the silver nanowires in withdrawal direction. The impact of this structural anisotropy on electrical anisotropy becomes more pronounced for low area coverage. The rod alignment does not influence the technical usability of the films as significant electrical anisotropy occurs only at optical transmission higher than 99 %. For films with lower transmission, electrical anisotropy becomes negligible. In addition to the experimental work, we have carried out computational studies in order to explain our findings further and compare them to our experiments and previous literature. This paper presents the first experimental observation of electrical anisotropy in two-dimensional silver nanowire networks close at the percolation threshold.Item Open Access Adaptive method for quantitative estimation of glucose and fructose concentrations in aqueous solutions based on infrared nanoantenna optics(2019) Schuler, Benjamin; Kühner, Lucca; Hentschel, Mario; Giessen, Harald; Tarín, CristinaIn life science and health research one observes a continuous need for new concepts and methods to detect and quantify the presence and concentration of certain biomolecules-preferably even in vivo or aqueous solutions. One prominent example, among many others, is the blood glucose level, which is highly important in the treatment of, e.g., diabetes mellitus. Detecting and, in particular, quantifying the amount of such molecular species in a complex sensing environment, such as human body fluids, constitutes a significant challenge. Surface-enhanced infrared absorption (SEIRA) spectroscopy has proven to be uniquely able to differentiate even very similar molecular species in very small concentrations. We are thus employing SEIRA to gather the vibrational response of aqueous glucose and fructose solutions in the mid-infrared spectral range with varying concentration levels down to 10 g/l. In contrast to previous work, we further demonstrate that it is possible to not only extract the presence of the analyte molecules but to determine the quantitative concentrations in a reliable and automated way. For this, a baseline correction method is applied to pre-process the measurement data in order to extract the characteristic vibrational information. Afterwards, a set of basis functions is fitted to capture the characteristic features of the two examined monosaccharides and a potential contribution of the solvent itself. The reconstruction of the actual concentration levels is then performed by superposition of the different basis functions to approximate the measured data. This software-based enhancement of the employed optical sensors leads to an accurate quantitative estimate of glucose and fructose concentrations in aqueous solutions.Item Open Access Radially polarized passively mode-locked thin-disk laser oscillator emitting sub-picosecond pulses with an average output power exceeding the 100 W level(2018) Beirow, Frieder; Eckerle, Michael; Dannecker, Benjamin; Dietrich, Tom; Abdou Ahmed, Marwan; Graf, ThomasWe report on a high-power passively mode-locked radially polarized Yb:YAG thin-disk oscillator providing 125 W of average output power. To the best of our knowledge, this is the highest average power ever reported from a mode-locked radially polarized oscillator without subsequent amplification stages. Mode-locking was achieved by implementing a SESAM as the cavity end mirror and the radial polarization of the LG*01 mode was obtained by means of a circular Grating Waveguide Output Coupler. The repetition rate was 78 MHz. A pulse duration of 0.97 ps and a spectral bandwidth of 1.4 nm (FWHM) were measured at the maximum output power. This corresponds to a pulse energy of 1.6 μJ and a pulse peak power of 1.45 MW. A high degree of radial polarization of 97.3 ± 1% and an M2-value of 2.16 which is close to the theoretical value for the LG*01 doughnut mode were measured.