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Authors: Brümmer, Franz
Brenner, Joachim
Bräuner, Thomas
Hülser, Dieter F.
Title: Effect of shock waves on suspended and immobilized L1210 cells
Issue Date: 1989 Zeitschriftenartikel Ultrasound in medicine & biology 15 (1989), S. 229-239. URL
Abstract: L1210 mouse leukemia cells have been exposed to different doses of shock waves generated by underwater spark discharge at 18 kV in an experimental lithotripter (XL1, Dornier). Histological and flow cytometric investigations revealed severe damage and a LD50 of about 420 shock waves when the cells were treated as suspensions. Cells immobilized in gelatine, however, were unaffected, indicating that secondary effects are responsible for the cellular damage. Possible mechanisms such as cavitation, jets, and shear forces are discussed.
Appears in Collections:04 Fakultät Energie-, Verfahrens- und Biotechnik

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