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http://dx.doi.org/10.18419/opus-1946
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DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Brümmer, Franz | de |
dc.contributor.author | Zempel, Günther | de |
dc.contributor.author | Bühle, Peter | de |
dc.contributor.author | Stein, Johannes-Christoph | de |
dc.contributor.author | Hülser, Dieter F. | de |
dc.date.accessioned | 2011-11-21 | de |
dc.date.accessioned | 2016-03-31T07:53:02Z | - |
dc.date.available | 2011-11-21 | de |
dc.date.available | 2016-03-31T07:53:02Z | - |
dc.date.issued | 1991 | de |
dc.identifier.other | 363846573 | de |
dc.identifier.uri | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-68876 | de |
dc.identifier.uri | http://elib.uni-stuttgart.de/handle/11682/1963 | - |
dc.identifier.uri | http://dx.doi.org/10.18419/opus-1946 | - |
dc.description.abstract | All-trans retinoic acid (RA), which was recently identified as a morphogen, affects gap junctional permeability in a dose- and time-dependent manner. In five different established mammalian cell lines (FL, BRL, BICR/M1Rk, HEL37, BT5C1) 100 μmol/liter RA reduced Lucifer yellow spreading within 30 min to 20-50% of the control. Ionic coupling, however, remained almost unaffected under the same conditions. Freezefractured membranes of untreated and RA-treated cells were similar with regard to frequency and sizes of gap junction plaques. With concentrations of less than 10 μmol/liter RA the dye spreading increased significantly in the human amniotic cell line FL, pointing to a possible modulatory effect of RA on junctional communication. | en |
dc.language.iso | en | de |
dc.rights | info:eu-repo/semantics/openAccess | de |
dc.subject.classification | Zellkultur , Gap junction , Retinoide | de |
dc.subject.ddc | 570 | de |
dc.title | Retinoic acid modulates gap junctional permeability: a comparative study of dye spreading and ionic coupling in cultured cells | en |
dc.type | article | de |
dc.date.updated | 2011-11-22 | de |
ubs.fakultaet | Fakultät Energie-, Verfahrens- und Biotechnik | de |
ubs.institut | Institut für Biomaterialien und biomolekulare Systeme | de |
ubs.opusid | 6887 | de |
ubs.publikation.source | Experimental cell research 196 (1991), S. 158-163. URL http://dx.doi.org./10.1016/0014-4827(91)90245-P | de |
ubs.publikation.typ | Zeitschriftenartikel | de |
Enthalten in den Sammlungen: | 04 Fakultät Energie-, Verfahrens- und Biotechnik |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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huel68.pdf | 3,74 MB | Adobe PDF | Öffnen/Anzeigen |
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