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Autor(en): Wollnik, Franziska
Titel: Strain differences in the pattern and intensity of wheel running activity in laboratory rats
Erscheinungsdatum: 1991
Dokumentart: Zeitschriftenartikel
Erschienen in: Experientia 47 (1991), S. 593-598. URL http://dx.doi.org./10.1007/BF01949883
URI: http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-92958
http://elib.uni-stuttgart.de/handle/11682/8239
http://dx.doi.org/10.18419/opus-8222
Zusammenfassung: Wheel running activity rhythms of three inbred rat strains, ACI/Ztm, BH/Ztm, and LEW/Ztm, were compared in order to evaluate the effect of genetic differences on circadian rhythm parameters. Significant strain differences were found in the general pattern of the activity rhythms and their characteristic periodicities as well as in the amount and duration of wheel running activity and the timing of activity onsets and offsets. The results suggest that genetic differences exist in the coupling of the multiple circadian oscillators that generate the overall pattern of wheel running activity.
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