Bitte benutzen Sie diese Kennung, um auf die Ressource zu verweisen:
http://dx.doi.org/10.18419/opus-828
Langanzeige der Metadaten
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Barth, Sandra | de |
dc.contributor.author | Fischer, Markus | de |
dc.contributor.author | Schmid, Rolf D. | de |
dc.contributor.author | Pleiss, Jürgen | de |
dc.date.accessioned | 2006-06-01 | de |
dc.date.accessioned | 2016-03-31T07:46:44Z | - |
dc.date.available | 2006-06-01 | de |
dc.date.available | 2016-03-31T07:46:44Z | - |
dc.date.issued | 2004 | de |
dc.identifier.other | 262545233 | de |
dc.identifier.uri | http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-26690 | de |
dc.identifier.uri | http://elib.uni-stuttgart.de/handle/11682/845 | - |
dc.identifier.uri | http://dx.doi.org/10.18419/opus-828 | - |
dc.description.abstract | The epoxide hydrolases and haloalkane dehalogenase database (EH/HD) integrates sequence and structure of a highly diverse protein family including mainly the Asp-hydrolases of EHs and HDs but also proteins like the Ser-hydrolases non-heme peroxidases, prolyl iminopetidases or 2-hydroxymuconic semialdehyde hydrolases. These proteins have a highly conserved structure, but display a remarkable diversity in sequence and function. 305 protein entries were assigned to 14 homologous families, forming two superfamilies. Annotated multisequence alignments and phylogenetic trees are provided for each homologous family and superfamily. Experimentally derived structures of 19 proteins are superposed and consistently annotated. Sequence and structure of all 305 proteins were systematically analysed. Thus, deeper insight is gained into the role of a highly conserved sequence motifs and structural elements. The EH/HD database is available at http://www.led.uni-stuttgart.de. | en |
dc.language.iso | en | de |
dc.rights | info:eu-repo/semantics/openAccess | de |
dc.subject.classification | Bioinformatik , Molekulare Bioinformatik , Proteindesign , Alignment <Biochemie> , Hydrolasen , Dehalogenasen | de |
dc.subject.ddc | 540 | de |
dc.subject.other | Sequence-structure-function relationship , sequence alignment , protein structure , phylogenetic analysis , GXGXS-motif | en |
dc.title | The database of epoxide hydrolases and haloalkane dehalogenases: one structure, many functions | en |
dc.type | preprint | de |
dc.date.updated | 2015-12-10 | de |
ubs.fakultaet | Fakultät Chemie | de |
ubs.institut | Institut für Technische Biochemie | de |
ubs.opusid | 2669 | de |
ubs.publikation.source | Bioinformatics 20 (2004), S. 2845-2847. URL http://dx.doi.org./10.1093/bioinformatics/bth284 | de |
ubs.publikation.typ | Preprint | de |
Enthalten in den Sammlungen: | 03 Fakultät Chemie |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
---|---|---|---|---|
Barth_2004a.pdf | 105,06 kB | Adobe PDF | Öffnen/Anzeigen |
Alle Ressourcen in diesem Repositorium sind urheberrechtlich geschützt.