Acquisition, but not retrieval of delayed alternation is impaired by ketamine

dc.contributor.authorHauber, Wolfgangde
dc.contributor.authorSchmidt, Werner J.de
dc.date.accessioned2009-12-15de
dc.date.accessioned2016-03-31T11:41:53Z
dc.date.available2009-12-15de
dc.date.available2016-03-31T11:41:53Z
dc.date.issued1990de
dc.description.abstractDissociative anaesthetics as ketamine and related drugs induce marked behavioral changes in rats, in particular behavioral stereotypies and learning impairments. In the resent study the effect of ketamine on acquisition and retrieval of a delayed alternation task was investigated. Results indicate that ketamine (8mg/kg i.p.) impaired specifically acquisition, while retrieval was not affected. Thus, stereotypies competing with ongoing behavior and therefore interfere with learning, appear not to be causative to the acquisition deficit, since retrieval should be affected in the same way. A possible involvement of NMDA receptors in deficient acquisition is discussed.en
dc.identifier.other318572486de
dc.identifier.urihttp://nbn-resolving.de/urn:nbn:de:bsz:93-opus-48933de
dc.identifier.urihttp://elib.uni-stuttgart.de/handle/11682/7097
dc.identifier.urihttp://dx.doi.org/10.18419/opus-7080
dc.language.isoende
dc.rightsinfo:eu-repo/semantics/openAccessde
dc.subject.classificationKetaminde
dc.subject.ddc610de
dc.titleAcquisition, but not retrieval of delayed alternation is impaired by ketamineen
dc.typearticlede
ubs.fakultaetFakultätsübergreifend / Sonstige Einrichtungde
ubs.institutSonstige Einrichtungde
ubs.opusid4893de
ubs.publikation.sourceResearch Communications in Psychology, Psychiatry and Behavior 15 (1990), S. 17-29de
ubs.publikation.typZeitschriftenartikelde

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