Blood pressure in rats : a comparison of a multifactorial experimental design to measurements in an outbred stock

Büttner, Dietmar; Hackbarth, Hansjoachim; Wollnik, Franziska; Borggreve, H.

Blood pressure in rats : a comparison of a multifactorial experimental design to measurements in an outbred stock

dc.contributor.author	Büttner, Dietmar	de
dc.contributor.author	Hackbarth, Hansjoachim	de
dc.contributor.author	Wollnik, Franziska	de
dc.contributor.author	Borggreve, H.	de
dc.date.accessioned	2014-05-21	de
dc.date.accessioned	2016-03-31T11:45:31Z
dc.date.available	2014-05-21	de
dc.date.available	2016-03-31T11:45:31Z
dc.date.issued	1984	de
dc.date.updated	2014-08-20	de
dc.description.abstract	Systolic blood pressure was measured in males of 8 inbred strains and 1 outbred stock of rats 5 times over a period of 20 min on 5 consecutive days. The strain means ranged between 107·9 mmHg and 149·3 mmHg. The estimated variance between strains (V = 248·7 mmHg) was about 5 times higher than the variance within strains (V = 54·3 mmHg). The intraindividual variance within strains was relatively constant (V = 24·0-37·6 mmHg), while the interindividual variance varied to a great extent (V = 4·5-44·5 mmHg) from strain to strain. The outbred stock showed values of blood pressure and components of variance similar to those of a single inbred strain. Thus, by investigation of a battery of 8 inbred strains in a multifactorial experimental design a greater phenotypic variability due to genetic strain differences is achieved than by measurements in a single outbred stock.	en
dc.identifier.other	412009684	de
dc.identifier.uri	http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-92912	de
dc.identifier.uri	http://elib.uni-stuttgart.de/handle/11682/8235
dc.identifier.uri	http://dx.doi.org/10.18419/opus-8218
dc.language.iso	en	de
dc.rights	info:eu-repo/semantics/openAccess	de
dc.subject.classification	Blutdruck , Züchtung , Ratte	de
dc.subject.ddc	590	de
dc.title	Blood pressure in rats : a comparison of a multifactorial experimental design to measurements in an outbred stock	en
dc.type	article	de
ubs.fakultaet	Fakultätsübergreifend / Sonstige Einrichtung	de
ubs.institut	Sonstige Einrichtung	de
ubs.opusid	9291	de
ubs.publikation.source	Laboratory animals 18 (1984), S. 110-114. URL http://dx.doi.org./10.1258/002367784780891334	de
ubs.publikation.typ	Zeitschriftenartikel	de

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