10 Fakultät Wirtschafts- und Sozialwissenschaften
Permanent URI for this collectionhttps://elib.uni-stuttgart.de/handle/11682/11
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Item Open Access Digital assessments of motor-cognitive performance in young and older adults : behavioral and neural correlates(2024) Park, Soo-Yong; Schott, Nadja (Prof. Dr.)Today's technological advances enable us to have a healthy life. Maintaining mental and physical health is one of the most critical aspects of our healthy life with increasing age. Moreover, one of the many ways to stay healthy is to detect problems of motor or cognitive impairment early and accurately in terms of assessment. Digital assessment can help uncover subtle differences in specific motor and cognitive declines. This early detection can lead to an adequate intervention on time, allowing for preliminary prevention before symptoms occur. From a different perspective, exercise effect on our bodies and minds is indescribable. Physical exercise induces cellular and molecular changes in our body, which positively change the structure and function of the brain. These positive changes in our brains can result in improved cognitive function. These effects are attributed to physical activity over a long-term period. However, understanding the acute effects of exercise-induced changes is also essential to potentially explain chronic effects. Also, identifying exercise-induced cortical activation patterns should be considered for cognitive function enhancements. For this reason, it is necessary to investigate the effect of exercise protocol composition, such as exercise intensity and duration, on cognitive function based on neural correlates. Based on these aspects, the present thesis is divided into two parts. In the first part (Part I: Assessment), the paper-pencil version of Trail-Making-Test (ppTMT), a neuropsychological assessment commonly used to investigate cognitive functions, was compared with the digital Trail-Making-Test (dTMT) developed on a tablet version. We verified its reliability and validity by comparing these two versions of TMT. Also, the dTMT was applied in patients with Parkinson's disease to detect subtle differences in fine motor and cognitive performance deterioration. As a strength of the dTMT, the measurement of additional variables for examining the applicability to the clinical field allowed the decomposition of cognitive abilities and observation of changes in performance during the task. The second part (Part II: exercise intervention) investigated the acute effects of exercise-induced cortical activation on cognitive performance using the dTMT. We used functional near-infrared spectroscopy (fNIRS) to measure hemodynamic response in the brain's frontal lobe and motor cortex for immediate and sustained effects of acute exercise with different exercise intensities. Finally, the interaction of these two parts (assessment and exercise intervention) and the neural mechanisms led to the following discussions. First, we confirmed the value of digital assessment as an early detection tool for motor and cognitive impairment. Second, we identified which exercise intervention positively induces cortical changes in our brain by accompanying the improvement of cognitive performance. The present thesis discussed the role of digital measurement and exercise intervention in maintaining our health and in which direction we should go for our future.Item Open Access Das untere Sprunggelenk als biomechanischer Einflussfaktor : Entwicklung und Anwendung eines IMU-Systems zur Beschreibung der Orientierung der Achsen des Sprunggelenks(2020) Schlechtweg, Sascha; Alt, Wilfried (Prof. Dr.)Item Open Access Effects of acute exercise at different intensities on fine motor‐cognitive dual‐task performance while walking : a functional near‐infrared spectroscopy study(2021) Park, Soo‐Yong; Reinl, Maren; Schott, NadjaStudies on the effects of acute exercises on cognitive functions vary greatly and depend on the duration and intensity of exercise and the type of cognitive tasks. This study aimed to investigate the neural correlates that underpin the acute effects of high‐intensity interval (HIIE) versus moderate‐intensity continuous exercise (MCE) on fine motor‐cognitive performance while walking (dual‐task, DT) in healthy young adults. Twenty‐nine healthy right‐handers (mean age: 25.1 years ± 4.04; 7 female) performed the digital trail‐making‐test (dTMT) while walking (5 km/h) before and after acute exercise. During task performance, the hemodynamic activation of the frontopolar area (FPA), dorsolateral prefrontal (DLPFC), and motor cortex (M1) was recorded using functional near‐infrared spectroscopy (fNIRS). Both HIIE and MCE resulted in improved dTMT performance, as reflected by an increase in the number of completed circles and a reduction in the time within and between circuits (reflecting improvements in working memory, inhibition, and decision making). Notably, HIIE evoked higher cortical activity on all brain areas measured in the present study than the MCE group. To our knowledge, these results provide the first empirical evidence using a mobile neuroimaging approach that both HIIE and MCE improve executive function during walking, likely mediated by increased activation of the task‐related area of the prefrontal cortex and the ability to effectively use, among other things, high fitness levels as neural enrichment resources.Item Open Access Associations of motor performance and executive functions: comparing children with Down syndrome to chronological and mental age-matched controls(2022) Klotzbier, Thomas J.; Holfelder, Benjamin; Schott, NadjaBackground. Children with Down syndrome (DS) exhibit lower motor and cognitive performance than typically developing children (TD). Although there is a relationship between these two developmental domains, only a few studies have addressed this association in children with DS compared to groups of the same chronological age (CA) or mental age (MA) within one study. This study aimed to fill this research gap. Method and Procedures. The Movement Assessment Battery for Children-2 and the Trail-Making Test was used to assess motor and cognitive performances in 12 children (M = 10.5 ± 10.08) with DS, 12 CA-matched, and 12 MA-matched controls. Results. There are significant group differences in the motor dimension (total test score; p < 0.001, η2p = 0.734), for processing speed (p < 0.001, η2p = 0.396), and cognitive flexibility (p < 0.001, η2p = 0.498). Between TD-CA and both other groups, the differences in the magnitude of correlations for the motor dimension balance are also significant (compared to DS: z = −2.489; p = 0.006, and to TD-MA: z = −3.12; p < 0.001). Conclusions. Our results suggest that the relationships depend on the studied cognitive and motor skills. It seems crucial to select a wide range of tasks for both domains that are as isolated as possible for future studies, to better understand the relationships between cognitive and motor skills in children with DS.Item Open Access Assessing basic and higher-level psychological needs satisfied through physical activity(2023) Dunton, Genevieve F.; Do, Bridgette; Crosley-Lyons, Rachel; Naya, Christine H.; Hewus, Micaela; Kanning, MartinaItem Open Access Influence of layer separation on the determination of stomach smooth muscle properties(2021) Borsdorf, Mischa; Böl, Markus; Siebert, TobiasUniaxial tensile experiments are a standard method to determine the contractile properties of smooth muscles. Smooth muscle strips from organs of the urogenital and gastrointestinal tract contain multiple muscle layers with different muscle fiber orientations, which are frequently not separated for the experiments. During strip activation, these muscle fibers contract in deviant orientations from the force-measuring axis, affecting the biomechanical characteristics of the tissue strips. This study aimed to investigate the influence of muscle layer separation on the determination of smooth muscle properties. Smooth muscle strips, consisting of longitudinal and circumferential muscle layers (whole-muscle strips [WMS]), and smooth muscle strips, consisting of only the circumferential muscle layer (separated layer strips [SLS]), have been prepared from the fundus of the porcine stomach. Strips were mounted with muscle fibers of the circumferential layer inline with the force-measuring axis of the uniaxial testing setup. The force–length (FLR) and force–velocity relationships (FVR) were determined through a series of isometric and isotonic contractions, respectively. Muscle layer separation revealed no changes in the FLR. However, the SLS exhibited a higher maximal shortening velocity and a lower curvature factor than WMS. During WMS activation, the transversally oriented muscle fibers of the longitudinal layer shortened, resulting in a narrowing of this layer. Expecting volume constancy of muscle tissue, this narrowing leads to a lengthening of the longitudinal layer, which counteracted the shortening of the circumferential layer during isotonic contractions. Consequently, the shortening velocities of the WMS were decreased significantly. This effect was stronger at high shortening velocities.Item Open Access Editorial - the stretch-shortening cycle of active muscle and muscle-tendon complex : what, why and how it increases muscle performance?(2021) Seiberl, Wolfgang; Hahn, Daniel; Power, Geoffrey A.; Fletcher, Jared R.; Siebert, TobiasItem Open Access Vertical jump kinetic parameters on sand and rigid surfaces in young female volleyball players with a combined background in indoor and beach volleyball(2023) Giatsis, George; Panoutsakopoulos, Vassilios; Frese, Christina; Kollias, Iraklis A.Little is known about the differences in vertical jump biomechanics executed on rigid (RJS) and sand (SJS) surfaces in female indoor and beach volleyball players. Eleven young female beach volleyball players with a combined indoor and beach volleyball sport background performed squat jumps, countermovement jumps with and without an arm swing, and drop jumps from 40 cm on a RJS (force plate) and SJS (sand pit attached to the force plate). The results of the 2 (surface) × 4 (vertical jump test) repeated-measure ANOVA revealed a significant (p < 0.05) main effect of the surface and the vertical jump test on the jump height and time to achieve peak vertical body center of mass velocity. A significant (p < 0.05) main effect of the test, but not of the surface (p > 0.05), was observed for the other examined biomechanical parameters. The only significant (p < 0.05) jump height gain difference between RJS and SJS was observed for the utilization of the stretch-shortening cycle, which was higher in SJS (15.4%) compared to RJS (7.5%). In conclusion, as the testing was conducted during the beach volleyball competitive season, the examined female players showed adaptations relating the effective utilization of the pre-stretch and enhanced stability during the execution of the vertical jump tests on a SJS compared to RJS.Item Open Access Upright posture control in changing gravity conditions(2021) Smirnov, EvgeniiIn order to be able to withstand and to take advantage of external forces and to be able to direct motor actions, living organisms developed ability to sense environmental impacts. For instance, proprioceptors and cutaneous receptors allow vertebrates to take into account, above all, gravitational influences. These receptors participate in planning and correcting posture, locomotion and other movements. In this thesis mechanisms of equilibrium control in changing gravity conditions were studied by means of literature analysis and analysis of data obtained in parabolic flight. This analysis revealed that standing balance in overloading is likely controlled in a manner resembling a single-link inverted pendulum. Such behavior could be beneficial to take advantage of passive body structures and to more actively involve foot receptors in balance regulation in challenging conditions. This adaptation also resembles typical postural responses in balance perturbation tasks. The latter were then studied in more detail. Further literature overview supported the suggestion that plantar foot receptors play an essential role in dynamic stability of upright posture. The obtained conclusions allowed to formulate possible mechanisms of sway and balance control and make suggestions on possible implementation of these mechanisms into the neuromusculoskeletal human model proposed by Walter, Gunther, Haeufle, and Schmitt (2021) in order to make equilibrium control of this model robuster.Item Open Access Profiles of motor-cognitive interference in Parkinson’s disease : the Trail-Walking Test to discriminate between motor phenotypes(2022) Klotzbier, Thomas J.; Schott, Nadja; Almeida, Quincy J.Background and Aims. Most research on Parkinson’s disease (PD) focuses on describing symptoms and movement characteristics. Studies rarely focus on the early detection of PD and the search for suitable markers of a prodromal stage. Early detection is important, so treatments that may potentially change the course of the disease can be attempted early on. While gait disturbances are less pronounced in the early stages of the disease, the prevalence, and severity increase with disease progression. Therefore, postural instability and gait difficulties could be identified as sensitive biomarkers. The aim was to evaluate the discriminatory power of the Trail-Walking Test (TWT; Schott, 2015) as a potential diagnostic instrument to improve the predictive power of the clinical evaluation concerning the severity of the disease and record the different aspects of walking. Methods. A total of 20 older healthy (M = 72.4 years, SD = 5.53) adults and 43 older adults with PD and the motor phenotypes postural instability/gait difficulty (PIGD; M = 69.7 years, SD = 8.68) and tremor dominant (TD; M = 68.2 years, SD = 8.94) participated in the study. The participants performed a motor-cognitive dual task (DT) of increasing cognitive difficulty in which they had to walk a given path (condition 1), walk to numbers in ascending order (condition 2), and walk to numbers and letters alternately and in ascending order (condition 3). Results. With an increase in the cognitive load, the time to complete the tasks (seconds) became longer in all groups, F(1.23, 73.5) = 121, p < 0.001, ɳ2p = 0.670. PIGD showed the longest times in all conditions of the TWT, F(2, 60) = 8.15, p < 0.001, ɳ2p = 0.214. Mutual interferences in the cognitive and motor domain can be observed. However, clear group-specific patterns cannot be identified. A differentiation between the motor phenotypes of PD is especially feasible with the purely motor condition (TWT-M; AUC = 0.685, p = 0.44). Conclusions. PD patients with PIGD must be identified by valid, well-evaluated clinical tests that allow for a precise assessment of the disease’s individual fall risk, the severity of the disease, and the prognosis of progression. The TWT covers various aspects of mobility, examines the relationship between cognitive functions and walking, and enables differentiation of the motor phenotypes of PD.